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Department of Cognitive Neurology

The Department of Cognitive Neurology is located at the University Medical Center Göttingen (UMG) and is headed by Prof. Dr. Melanie Wilke. Our department hosts the core facility MR-Research in Neurosciences headed by PD Dr. Peter Dechent. The Cognitive Neurology Group at the DPZ is a satellite of our department at the UMG.

We aim to understand the neural basis of conscious perception and how it relates to the selection and execution of action plans. Our research applies a multi-modal approach that combines causal brain perturbation methods with fMRI and electrophysiological recordings in healthy humans and patients suffering from e.g. stroke.

German Primate Center: Decision and Awareness Group

University Medical Center: Core Facility MR-Research

Publications

  • Dorsal pulvinar inactivation leads to spatial selection bias without perceptual deficit

Kaduk K, Wilke M, Kagan I.

Sci Rep. 2024 Jun 4;14(1):12852. doi: 10.1038/s41598-024-62056-5. PMID: 38834578 Free PMC article.

  • Visual, delay, and oculomotor timing and tuning in macaque dorsal pulvinar during instructed and free choice memory saccades.

Schneider, L., Dominguez-Vargas, A.-U., Gibson, L., Wilke, M., Kagan, I., 2023.

Cereb. Cortex N. Y. N 1991 33, 10877–10900. doi.org/10.1093/cercor/bhad333

  • Visuospatial and motor deficits following pulvinar lesions, in: The Cerebral Cortex and Thalamus

Wilke, M, Kagan, I., 2023. (Eds.: Usrey, M. & Murray Sherman).

Oxford University Press, pp. 764–775. ISBN: 978-0197676158

  • Detection of tACS aftereffects is improved by considering the individual electric field strength and self-rated sleepiness.

Steinmann I, Williams KA, Wilke M, Antal A. Frontiers in Neuroscience. 2022. (in press)

  • Detection of Transcranial Alternating Current Stimulation Aftereffects Is Improved by Considering the Individual Electric Field Strength and Self-Rated Sleepiness.

Steinmann I, Williams KA, Wilke M, Antal A.Front Neurosci. 2022 Jun 27;16:870758. doi: 10.3389/fnins.2022.870758. eCollection 2022. PMID: 35833087 Free PMC article.

  • Toward next-generation primate neuroscience: A collaboration-based strategic plan for integrative neuroimaging. 

Milham M, Petkov C, ... Wilke M, ...Zuo Z. Neuron. 2022. Jan 5;110(1):16-20

  • Detection of tACS aftereffects is improved by considering the individual electric field strength and self-rated sleepiness. 

Steinmann I, Williams KA, Wilke M, Antal A. Frontiers in Neuroscience. 2022. (in press)

  • Combined Brain Pertubation and Neuroimaging in Non-human Primates. 

Klink PC, Aubry JF, Ferrera VP, ... Wilke M, Kagan I, Petkov CI. Neuroimage. 2021. 235, 118017.

  • Effective connectivity and spatial selectivity-dependent fMRI changes elicited by microstimulation of pulvinar and LIP. 

Kagan I*, Gibson L*, Spanou E, Wilke M. Neuroimage. 2021. 118283.

  • Reduced alpha amplitudes predict perceptual suppression. 

Poland E, Bhonsle A, Steinmann I, Wilke M. Scientific Reports 11 2021. s41598-021-92404-8.

  • Eye position signals in the dorsal pulvinar during fixation and goal-directed saccades.

Schneider L, Dominguez-Vargas A, Gibson L, Kagan I*, Wilke M*. Journal of Neurophysiology. 2020 Jan 1;123(1):367-391.

  • Aberrant functional connectivity of resting state networks related to misperceptions and intra-individual variability in Parkinson‘s disease. 

Miloserdov K, Schmidt-Samoa C, Williams C, Weinrich CA, Bürk K, Kagan I, Trenkwalder C, Bähr M, Wilke M. Neuroimage: Clinical. 2020;25:102076.

  • Probing the link between perception and oscillations: Lessons from transcranial alternating current stimulation. 

Cabral-Calderin Y, Wilke M. Neuroscientist. 2020. Feb 7: 1073858419828646.

  • Reach and grasp deficits following damage to the dorsal pulvinar. 

Wilke M, Schneider L, Dominguez-Vargas A, Schmidt-Samoa C, Miloserdov K, Nazzal A, Cabral-Calderin Y, Dechent P, Scherberger H, Kagan I, Bähr M. Cortex. 2018. 99:135-149.

  • Simultaneous transcranial alternating current stimulation and functional magnetic resonance imaging.

Williams KA, Cabral-Calderin Y, Schmidt-Samoa C, Weinrich C, Dechent P, Wilke M. J Vis Exp. 2017. Jun 5 (124).

  • Electrical Microstimulation of the Pulvinar Biases Saccade Choices and Reaction Times in a Time-Dependent Manner.

Dominguez-Vargas A, Schneider L, Wilke M*, Kagan I*. Journal of Neuroscience. 2017. Feb 22;37(8):2234-2257.

  • Consciousness regained: disentangling mechanisms, brain systems, and behavioral responses.

Storm F, Boly M, Casali M, Massimini M, Olcese M, Pennartz, C.M.A., Wilke, M. Journal of Neuroscience. 2017. 8;37(45):10882-10893.

  • Transcranial alternating current stimulation modulates spontaneous low frequency fluctuations as measured with fMRI. 

Cabral-Calderin Y*, Williams K*, Dechent P, Opitz A, Wilke M. Neuroimage. 2016 Jul 5. S1053-8119(16)30312-3.

  • Rhythmic gamma stimulation affects bistable perception. 

Cabral-Calderin Y, Schmidt-Samoa C, Wilke M. Journal of Cognitive Neuroscience. 2015. 20:1-10.

  • No-report paradigms: Extracting the true neural correlates of consciousness. Trends in 

Tsuchiya N, Wilke M, Frässle S, Lamme V. Cognitive Sciences. 2015. Dec;19(12):757-70.